• 靶点：
• Gγ 5

• 简介：
• >>Ras signaling pathway;>>Chemokine signaling pathway;>>PI3K-Akt signaling pathway;>>Apelin signaling pathway;>>Circadian entrainment;>>Retrograde endocannabinoid signaling;>>Glutamatergic synapse;>>Cholinergic synapse;>>Serotonergic synapse;>>GABAergic synapse;>>Dopaminergic synapse;>>Relaxin signaling pathway;>>Morphine addiction;>>Alcoholism;>>Human cytomegalovirus infection;>>Kaposi sarcoma-associated herpesvirus infection;>>Human immunodeficiency virus 1 infection;>>Pathways in cancer

• 基因名称：
• GNG5

• 蛋白名称：
• Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5

• Human Gene Id：
• 2787

• Human Swiss Prot No：
• P63218

• Mouse Gene Id：
• 1.00044e+008

• Mouse Swiss Prot No：
• Q80SZ7

• Rat Gene Id：
• 1.0036e+008

• Rat Swiss Prot No：
• P63219

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human GNG5. AA range:10-59

• 特异性：
• Gγ 5 Polyclonal Antibody detects endogenous levels of Gγ 5 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• GNG5;GNGT5;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5

• 分子量：
• 7kD

• 背景：
• G protein subunit gamma 5(GNG5) Homo sapiens G proteins are trimeric (alpha-beta-gamma) membrane-associated proteins that regulate flow of information from cell surface receptors to a variety of internal metabolic effectors. Interaction of a G protein with its activated receptor promotes exchange of GTP for GDP that is bound to the alpha subunit. The alpha-GTP complex dissociates from the beta-gamma heterodimer so that the subunits, in turn, may interact with and regulate effector molecules (Gilman, 1987 [PubMed 3113327]; summary by Ahmad et al., 1995) [PubMed 7606925].[supplied by OMIM, Nov 2010],

• 功能：
• function:Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.,similarity:Belongs to the G protein gamma family.,subunit:G proteins are composed of 3 units, alpha, beta and gamma.,

• 细胞定位：
• Cell membrane ; Lipid-anchor ; Cytoplasmic side .

• 组织表达：
• Brain,Platelet,Umbilical cord blood,

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