GRK 7 Polyclonal Antibody
- 货号：YT2072
- 应用：WB;IF;ELISA
- 种属：Human
- 简介：
- >>Chemokine signaling pathway;>>Endocytosis;>>Phototransduction
- 蛋白名称：
- G protein-coupled receptor kinase 7
- 免疫原：
- The antiserum was produced against synthesized peptide derived from human GRK7. AA range:371-420
- 特异性：
- GRK 7 Polyclonal Antibody detects endogenous levels of GRK 7 protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- GRK7;GPRK7;G protein-coupled receptor kinase 7;G protein-coupled receptor kinase GRK7
- 背景：
- This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. It is specifically expressed in the retina and the encoded protein has been shown to phosphorylate cone opsins and initiate their deactivation. [provided by RefSeq, Jul 2008],
- 功能：
- catalytic activity:ATP + [G-protein-coupled receptor] = ADP + [G-protein-coupled receptor] phosphate.,function:Phosphorylates cone opsins thereby initiating their deactivation.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 RGS domain.,tissue specificity:Retina. Cones and rod.,
- 细胞定位：
- Membrane ; Lipid-anchor .
- 组织表达：
- Retinal cones, outer and inner segments.
- Western Blot analysis of various cells using GRK 7 Polyclonal Antibody
- Western blot analysis of lysates from COLO205, Jurkat, and HeLa cells, using GRK7 Antibody. The lane on the right is blocked with the synthesized peptide.
