• 靶点：
• GPR75

• 基因名称：
• GPR75

• 蛋白名称：
• Probable G-protein coupled receptor 75

• Human Gene Id：
• 10936

• Human Swiss Prot No：
• O95800

• Mouse Gene Id：
• 237716

• Mouse Swiss Prot No：
• Q6X632

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human GPR75. AA range:381-430

• 特异性：
• GPR75 Polyclonal Antibody detects endogenous levels of GPR75 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• GPR75;Probable G-protein coupled receptor 75

• 实测条带：
• 59kD

• 背景：
• GPR75 is a member of the G protein-coupled receptor family. GPRs are cell surface receptors that activate guanine-nucleotide binding proteins upon the binding of a ligand.[supplied by OMIM, Jul 2002],

• 功能：
• function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed at high levels in brain and spinal cord and at detectable levels in retinal pigment epithelium. In situ hybridization of adult eye sections localized transcripts only to the perivascular cells, surrounding retinal arterioles, in the ganglion cell/nerve fiber layer.,

• 细胞定位：
• Cell membrane; Multi-pass membrane protein .

• 组织表达：
• Expressed at high levels in brain and spinal cord and at detectable levels in retinal pigment epithelium. In situ hybridization of adult eye sections localized transcripts only to the perivascular cells, surrounding retinal arterioles, in the ganglion cell/nerve fiber layer. Also expressed by islet cells (at protein level).

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