GPR48 Polyclonal Antibody
- 货号:YT2023
- 应用:WB;IF;ELISA
- 种属:Human;Rat;Mouse;
- 简介:
- >>Wnt signaling pathway
- 蛋白名称:
- Leucine-rich repeat-containing G-protein coupled receptor 4
- 免疫原:
- The antiserum was produced against synthesized peptide derived from human LGR4. AA range:461-510
- 特异性:
- GPR48 Polyclonal Antibody detects endogenous levels of GPR48 protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- LGR4;GPR48;Leucine-rich repeat-containing G-protein coupled receptor 4;G-protein coupled receptor 48
- 背景:
- The protein encoded by this gene is a G-protein coupled receptor that binds R-spondins and activates the Wnt signaling pathway. This Wnt signaling pathway activation is necessary for proper development of many organs of the body. [provided by RefSeq, Oct 2016],
- 功能:
- function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 1 family.,similarity:Contains 15 LRR (leucine-rich) repeats.,tissue specificity:Expressed in multiple steroidogenic tissues: placenta, ovary, testis and adrenal. Expressed also in spinal cord, thyroid, stomach, trachea, heart, pancreas, kidney, prostate and spleen.,
- 细胞定位:
- Cell membrane ; Multi-pass membrane protein .
- 组织表达:
- Expressed in multiple steroidogenic tissues: placenta, ovary, testis and adrenal. Expressed also in spinal cord, thyroid, stomach, trachea, heart, pancreas, kidney, prostate and spleen.
![](/uploadfiles/PIC/yt2023_pic852518522.jpg)
- Western blot analysis of lysates from Jurkat cells, using LGR4 Antibody. The lane on the right is blocked with the synthesized peptide.