GPR17 Polyclonal Antibody
- 货号:YT1992
- 应用:WB;IF;ELISA
- 种属:Human;Mouse;Rat
- 蛋白名称:
- Uracil nucleotide/cysteinyl leukotriene receptor
- 免疫原:
- The antiserum was produced against synthesized peptide derived from human GPR17. AA range:196-245
- 特异性:
- GPR17 Polyclonal Antibody detects endogenous levels of GPR17 protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- GPR17;Uracil nucleotide/cysteinyl leukotriene receptor;UDP/CysLT receptor;G-protein coupled receptor 17;P2Y-like receptor;R12
- 背景:
- function:Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain.,
- 功能:
- function:Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain.,
- 细胞定位:
- Cell membrane; Multi-pass membrane protein.
- 组织表达:
- Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain.
![](/uploadfiles/PIC/yt1992_pic832718522.jpg)
- Immunofluorescence analysis of HeLa cells, using GPR17 Antibody. The picture on the right is blocked with the synthesized peptide.