GPR133 Polyclonal Antibody
- 货号:YT1969
- 应用:WB;IF;ELISA
- 种属:Human;Monkey
- 蛋白名称:
- Probable G-protein coupled receptor 133
- 免疫原:
- The antiserum was produced against synthesized peptide derived from human GPR133. AA range:461-510
- 特异性:
- GPR133 Polyclonal Antibody detects endogenous levels of GPR133 protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- GPR133;PGR25;Probable G-protein coupled receptor 133;G-protein coupled receptor PGR25
- 背景:
- The adhesion G-protein-coupled receptors (GPCRs), including GPR133, are membrane-bound proteins with long N termini containing multiple domains. GPCRs, or GPRs, contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins (summary by Bjarnadottir et al., 2004 [PubMed 15203201]).[supplied by OMIM, Nov 2010],
- 功能:
- function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 GPS domain.,
- 细胞定位:
- Cell membrane ; Multi-pass membrane protein .
- 组织表达:
- Up-regulated in CD133(+) cell population of glioblastoma.
![](/uploadfiles/PIC/yt1969_pic843918522.jpg)
- Immunofluorescence analysis of HeLa cells, using GPR133 Antibody. The picture on the right is blocked with the synthesized peptide.
![](/uploadfiles/PIC/yt1969_pic844018522.jpg)
- Western blot analysis of lysates from COS7 cells, using GPR133 Antibody. The lane on the right is blocked with the synthesized peptide.
![](/uploadfiles/PIC/yt1969_pic993018522.jpg)
- Western blot analysis of the lysates from K562 cells using GPR133 antibody.