GPR126 Polyclonal Antibody
- 货号:YT1967
- 应用:WB;IHC;IF;ELISA
- 种属:Human;Rat;Mouse;
- 蛋白名称:
- G-protein coupled receptor 126
- 免疫原:
- The antiserum was produced against synthesized peptide derived from human GPR126. AA range:431-480
- 特异性:
- GPR126 Polyclonal Antibody detects endogenous levels of GPR126 protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- GPR126;DREG;VIGR;G-protein coupled receptor 126;Developmentally regulated G-protein-coupled receptor;Vascular inducible G protein-coupled receptor
- 背景:
- This gene, which is upregulated in human umbilical vein endothelial cells, encodes a G protein-coupled receptor. Variations in this gene can affect a person's stature. Multiple transcript variants encoding different proteins have been found for this gene. [provided by RefSeq, Mar 2009],
- 功能:
- function:Orphan receptor.,polymorphism:Genetic variations in GPR126 influences stature as a quantitative trait (STQTL) [MIM:606255]. Adult height is an easily observable and highly heritable complex continuous trait. Because of this, it is a model trait for studying genetic influence on quantitative traits.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 CUB domain.,similarity:Contains 1 GPS domain.,similarity:Contains 1 pentaxin domain.,
- 细胞定位:
- Cell membrane ; Multi-pass membrane protein . Detected on the cell surface of activated but not resting umbilical vein. .
- 组织表达:
- Expressed in placenta and to a lower extent in pancreas and liver. Detected in aortic endothelial cells but not in skin microvascular endothelial cells.
![](/uploadfiles/PIC/yt1967-wb.jpg)
- Western Blot analysis of various cells using GPR126 Polyclonal Antibody diluted at 1:500
![](/uploadfiles/PIC/yt1967_pic843718522.jpg)
- Western blot analysis of lysates from HUVEC cells, using GPR126 Antibody. The lane on the right is blocked with the synthesized peptide.
![](/uploadfiles/PIC/7-ihc-ganaicm202207.jpg)
- Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).