GPR105 Polyclonal Antibody
- 货号:YT1952
- 应用:WB;IHC;IF;ELISA
- 种属:Human;Mouse;Rat
- 简介:
- >>Neuroactive ligand-receptor interaction
- 蛋白名称:
- P2Y purinoceptor 14
- 免疫原:
- The antiserum was produced against synthesized peptide derived from human GPR105. AA range:146-195
- 特异性:
- GPR105 Polyclonal Antibody detects endogenous levels of GPR105 protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- P2RY14;GPR105;KIAA0001;P2Y purinoceptor 14;P2Y14;G-protein coupled receptor 105;UDP-glucose receptor
- 背景:
- The product of this gene belongs to the family of G-protein coupled receptors, which contains several receptor subtypes with different pharmacological selectivity for various adenosine and uridine nucleotides. This receptor is a P2Y purinergic receptor for UDP-glucose and other UDP-sugars coupled to G-proteins. It has been implicated in extending the known immune system functions of P2Y receptors by participating in the regulation of the stem cell compartment, and it may also play a role in neuroimmune function. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008],
- 功能:
- function:Receptor for UDP-glucose and other UDP-sugar coupled to G-proteins. Not activated by ATP, ADP, UTP or ATP.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Highest expression in the placenta, adipose tissue, stomach and intestine, intermediate levels in the brain, spleen, lung and heart, lowest levels in the kidney.,
- 细胞定位:
- Cell membrane; Multi-pass membrane protein.
- 组织表达:
- Highest expression in the placenta, adipose tissue, stomach and intestine, intermediate levels in the brain, spleen, lung and heart, lowest levels in the kidney.
![](/uploadfiles/PIC/yt1952-wb.jpg)
- Western Blot analysis of various cells using GPR105 Polyclonal Antibody
![](/uploadfiles/PIC/yt1952_pic830318522.jpg)
- Immunofluorescence analysis of MCF7 cells, using GPR105 Antibody. The picture on the right is blocked with the synthesized peptide.
![](/uploadfiles/PIC/yt1952_pic830418522.jpg)
- Western blot analysis of lysates from 293, COLO205, and HepG2 cells, using GPR105 Antibody. The lane on the right is blocked with the synthesized peptide.
![](/uploadfiles/PIC/yt1952_pic992318522.jpg)
- Western blot analysis of the lysates from K562 cells using GPR105 antibody.