GPR10 Polyclonal Antibody
- 货号：YT1946
- 应用：WB;IF;ELISA
- 种属：Human;Mouse;Rat
- 简介：
- >>Neuroactive ligand-receptor interaction
- 蛋白名称：
- Prolactin-releasing peptide receptor
- 免疫原：
- The antiserum was produced against synthesized peptide derived from human PRLHR. AA range:184-233
- 特异性：
- GPR10 Polyclonal Antibody detects endogenous levels of GPR10 protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- PRLHR;GPR10;GR3;Prolactin-releasing peptide receptor;PrRP receptor;PrRPR;G-protein coupled receptor 10;hGR3
- 背景：
- PRLHR is a 7-transmembrane domain receptor for prolactin-releasing hormone (PRLH; MIM 602663) that is highly expressed in anterior pituitary (Ozawa et al., 2002 [PubMed 11923475]).[supplied by OMIM, Mar 2008],
- 功能：
- function:Receptor for prolactin-releasing peptide (PrRP). Implicated in lactation, regulation of food intake and pain-signal processing.,induction:Repressed by bromocriptine, a dopamine agonist.,similarity:Belongs to the G-protein coupled receptor 1 family.,subunit:Interacts through its C-terminal region with the PDZ domain-containing proteins GRIP1, GRIP2 and PICK1. Interacts with PDZ domains 4 and 5 of GRIP1 and with the PDZ domain of PICK1.,tissue specificity:Only detected in the pituitary gland and in all cell types of pituitary adenomas.,
- 细胞定位：
- Cell membrane; Multi-pass membrane protein.
- 组织表达：
- Only detected in the pituitary gland and in all cell types of pituitary adenomas.
- Western blot analysis of lysates from Jurkat cells, using PRLHR Antibody. The lane on the right is blocked with the synthesized peptide.
