GNL1 Polyclonal Antibody

    • 货号:YT1937
    • 应用:WB;ELISA
    • 种属:Human;Mouse;Rat
      • 靶点:
      • GNL1
      • 基因名称:
      • GNL1
      • 蛋白名称:
      • Guanine nucleotide-binding protein-like 1
      • Human Gene Id:
      • 2794
      • Human Swiss Prot No:
      • P36915
      • Mouse Swiss Prot No:
      • P36916
      • 免疫原:
      • The antiserum was produced against synthesized peptide derived from human GNL1. AA range:61-110
      • 特异性:
      • GNL1 Polyclonal Antibody detects endogenous levels of GNL1 protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • GNL1;HSR1;Guanine nucleotide-binding protein-like 1;GTP-binding protein HSR1
      • 实测条带:
      • 69kD
      • 背景:
      • The GNL1 gene, identified in the human major histocompatibility complex class I region, shows a high degree of similarity with its mouse counterpart. The GNL1 gene is located less than 2 kb centromeric to HLA-E, in the same transcriptional orientation. GNL1 is telomeric to HLA-B and HLA-C. [provided by RefSeq, Jul 2008],
      • 功能:
      • domain:In contrast to other GTP-binding proteins, this family is characterized by a circular permutation of the GTPase motifs described by a G4-G1-G3 pattern.,function:Possible regulatory or functional link with the histocompatibility cluster.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the MMR1/HSR1 GTP-binding protein family.,
      • 细胞定位:
      • extracellular space,nucleus,
      • 组织表达:
      • Cervix,Muscle,Peripheral blood leukocyte,Skin,T-cell,
      • 产品图片
      • Western Blot analysis of various cells using GNL1 Polyclonal Antibody
      • Western Blot analysis of K562 cells using GNL1 Polyclonal Antibody
      • Western blot analysis of lysates from Jurkat, LOVO, and K562 cells, using GNL1 Antibody. The lane on the right is blocked with the synthesized peptide.