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WB 试剂
- PonceauS Staining Solution
- PBST Washing Buffer, 10X
- 1.5M Tris-HCl Buffer, pH8.8
- 1M Tris-HCl Buffer, pH6.8
- 10% SDS Solution
- Prestained Protein Marker
- TBST Washing Buffer, 10X
- SDS PAGE Loading Buffer, 5X
- Stripping Buffered Solution
- Tris Buffer, pH7.4, 10X
- Total Protein Extraction Kit
- Running Buffer, 10X
- Transfer Buffer, 10X
- 30% Acr-Bis(29:1) Solution
- Tris电泳液速溶颗粒
- PBS(1X, premixed powder)
- TBS(1X, premixed powder)
- 快速封闭液
- 转膜液速溶颗粒
- Chemical reagents
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GLK Polyclonal Antibody
- 货号:YT1915
- 应用:WB;ELISA
- 种属:Human;Mouse;Rat
- 简介:
- >>MAPK signaling pathway
- 蛋白名称:
- Mitogen-activated protein kinase kinase kinase kinase 3
- 免疫原:
- The antiserum was produced against synthesized peptide derived from human MAP4K3. AA range:10-59
- 特异性:
- GLK Polyclonal Antibody detects endogenous levels of GLK protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- MAP4K3;RAB8IPL1;Mitogen-activated protein kinase kinase kinase kinase 3;Germinal center kinase-related protein kinase;GLK;MAPK/ERK kinase kinase kinase 3;MEK kinase kinase 3;MEKKK 3
- 背景:
- mitogen-activated protein kinase kinase kinase kinase 3(MAP4K3) Homo sapiens This gene encodes a member of the mitogen-activated protein kinase kinase kinase kinase family. The encoded protein activates key effectors in cell signalling, among them c-Jun. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012],
- 功能:
- catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,function:May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 CNH domain.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with SH3GL2. Interaction appears to regulate MAP4K3-mediated JNK activation.,tissue specificity:Ubiquitously expressed in all tissues examined, with high levels in heart, brain, placenta, skeletal muscle, kidney and pancreas and lower levels in lung and liver.,
- 细胞定位:
- intracellular,cytoplasm,
- 组织表达:
- Ubiquitously expressed in all tissues examined, with high levels in heart, brain, placenta, skeletal muscle, kidney and pancreas and lower levels in lung and liver.
![](/uploadfiles/PIC/yt1915-wb.jpg)
- Western Blot analysis of various cells using GLK Polyclonal Antibody
![](/uploadfiles/PIC/yt1915_pic557618522.jpg)
- Western blot analysis of lysates from HepG2 and K562 cells, using MAP4K3 Antibody. The lane on the right is blocked with the synthesized peptide.