• 靶点：
• GBP1

• 简介：
• >>NOD-like receptor signaling pathway

• 基因名称：
• GBP1

• 蛋白名称：
• Interferon-induced guanylate-binding protein 1

• Human Gene Id：
• 2633

• Human Swiss Prot No：
• P32455

• Mouse Swiss Prot No：
• Q01514

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human GBP1. AA range:71-120

• 特异性：
• GBP1 Polyclonal Antibody detects endogenous levels of GBP1 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• GBP1;Interferon-induced guanylate-binding protein 1;GTP-binding protein 1;GBP-1;HuGBP-1;Guanine nucleotide-binding protein 1

• 实测条带：
• 68kD

• 背景：
• Guanylate binding protein expression is induced by interferon. Guanylate binding proteins are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP) and are distinguished from the GTP-binding proteins by the presence of 2 binding motifs rather than 3. [provided by RefSeq, Jul 2008],

• 功能：
• function:Binds GTP, GDP and GMP.,induction:By interferon gamma during macrophage activation.,similarity:Belongs to the GBP family.,

• 细胞定位：
• Cytoplasm . Golgi apparatus membrane; Lipid-anchor ; Cytoplasmic side. Cell membrane . Secreted . Cytoplasmic vesicle . Secreted from endothelial cells in the cerebrospinal fluid, upon bacterial challenge and independently of IFNG induction. Golgi membrane localization requires isoprenylation and the presence of another IFNG-induced factor.

• 组织表达：
• Placenta,Spleen,Uterus,

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