• 靶点：
• GATA-6

• 基因名称：
• GATA6

• 蛋白名称：
• Transcription factor GATA-6

• Human Gene Id：
• 2627

• Human Swiss Prot No：
• Q92908

• Mouse Gene Id：
• 14465

• Mouse Swiss Prot No：
• Q61169

• Rat Gene Id：
• 29300

• Rat Swiss Prot No：
• P46153

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human GATA6. AA range:461-510

• 特异性：
• GATA-6 Polyclonal Antibody detects endogenous levels of GATA-6 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• GATA6;Transcription factor GATA-6;GATA-binding factor 6

• 实测条带：
• 45kD

• 背景：
• This gene is a member of a small family of zinc finger transcription factors that play an important role in the regulation of cellular differentiation and organogenesis during vertebrate development. This gene is expressed during early embryogenesis and localizes to endo- and mesodermally derived cells during later embryogenesis and thereby plays an important role in gut, lung, and heart development. Mutations in this gene are associated with several congenital defects. [provided by RefSeq, Mar 2012],

• 功能：
• function:Thought to be important for regulating terminal differentiation and/or proliferation.,similarity:Contains 2 GATA-type zinc fingers.,tissue specificity:Expressed in heart, gut and gut-derived tissues.,

• 细胞定位：
• Nucleus .

• 组织表达：
• Expressed in heart, gut and gut-derived tissues. Expressed in skin upper pilosebaceous unit. Expression is decreased or lost in acne lesions (PubMed:33082341).

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