GALR1 Polyclonal Antibody

    • 货号:YT1844
    • 应用:IF;ELISA
    • 种属:Human;Mouse
      • 靶点:
      • GALR1
      • 简介:
      • >>Neuroactive ligand-receptor interaction
      • 基因名称:
      • GALR1
      • 蛋白名称:
      • Galanin receptor type 1
      • Human Gene Id:
      • 2587
      • Human Swiss Prot No:
      • P47211
      • Mouse Swiss Prot No:
      • P56479
      • 免疫原:
      • The antiserum was produced against synthesized peptide derived from human GALR1. AA range:161-210
      • 特异性:
      • GALR1 Polyclonal Antibody detects endogenous levels of GALR1 protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • GALR1;GALNR;GALNR1;Galanin receptor type 1;GAL1-R;GALR-1
      • 分子量:
      • 39kD
      • 背景:
      • The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart. [provided by RefSeq, Jul 2008],
      • 功能:
      • function:Receptor for the hormone galanin. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.,PTM:Palmitoylated on at least one of the three cysteine residues present in the C-terminal part.,similarity:Belongs to the G-protein coupled receptor 1 family.,
      • 细胞定位:
      • Cell membrane; Multi-pass membrane protein.
      • 组织表达:
      • Brain,Melanoma,Small intestine,
      • 产品图片
      • Immunofluorescence analysis of LOVO cells, using GALR1 Antibody. The picture on the right is blocked with the synthesized peptide.