GALR1 Polyclonal Antibody
- 货号:YT1844
- 应用:IF;ELISA
- 种属:Human;Mouse
- 简介:
- >>Neuroactive ligand-receptor interaction
- 蛋白名称:
- Galanin receptor type 1
- 免疫原:
- The antiserum was produced against synthesized peptide derived from human GALR1. AA range:161-210
- 特异性:
- GALR1 Polyclonal Antibody detects endogenous levels of GALR1 protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- GALR1;GALNR;GALNR1;Galanin receptor type 1;GAL1-R;GALR-1
- 背景:
- The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart. [provided by RefSeq, Jul 2008],
- 功能:
- function:Receptor for the hormone galanin. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.,PTM:Palmitoylated on at least one of the three cysteine residues present in the C-terminal part.,similarity:Belongs to the G-protein coupled receptor 1 family.,
- 细胞定位:
- Cell membrane; Multi-pass membrane protein.
- 组织表达:
- Brain,Melanoma,Small intestine,
- Immunofluorescence analysis of LOVO cells, using GALR1 Antibody. The picture on the right is blocked with the synthesized peptide.