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WB 试剂
- PonceauS Staining Solution
- PBST Washing Buffer, 10X
- 1.5M Tris-HCl Buffer, pH8.8
- 1M Tris-HCl Buffer, pH6.8
- 10% SDS Solution
- Prestained Protein Marker
- TBST Washing Buffer, 10X
- SDS PAGE Loading Buffer, 5X
- Stripping Buffered Solution
- Tris Buffer, pH7.4, 10X
- Total Protein Extraction Kit
- Running Buffer, 10X
- Transfer Buffer, 10X
- 30% Acr-Bis(29:1) Solution
- Tris电泳液速溶颗粒
- PBS(1X, premixed powder)
- TBS(1X, premixed powder)
- 快速封闭液
- 转膜液速溶颗粒
- Chemical reagents
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Gads Polyclonal Antibody
- 货号:YT1833
- 应用:WB;ELISA
- 种属:Human;Mouse
- 简介:
- >>T cell receptor signaling pathway
- 蛋白名称:
- GRB2-related adapter protein 2
- 免疫原:
- The antiserum was produced against synthesized peptide derived from human GRAP2. AA range:121-170
- 特异性:
- Gads Polyclonal Antibody detects endogenous levels of Gads protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- GRAP2;GADS;GRB2L;GRID;GRB2-related adapter protein 2;Adapter protein GRID;GRB-2-like protein;GRB2L;GRBLG;GRBX;Grf40 adapter protein;Grf-40;Growth factor receptor-binding protein;Hematopoietic cell-associated adapter protein Grp
- 背景:
- This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Apr 2014],
- 功能:
- function:Interacts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated shc.,similarity:Belongs to the GRB2/sem-5/DRK family.,similarity:Contains 1 SH2 domain.,similarity:Contains 2 SH3 domains.,subunit:Interacts with phosphorylated LIME1 upon TCR activation (By similarity). Interacts with phosphorylated LAT and LAX1 upon TCR activation. Interacts with SHB.,
- 细胞定位:
- Nucleus . Cytoplasm . Endosome .
- 组织表达:
- Blood,Lung,Platelet,Spleen,T-cell,Thymus,
![](/uploadfiles/PIC/yt1833-wb.jpg)
- Western Blot analysis of various cells using Gads Polyclonal Antibody
![](/uploadfiles/PIC/yt1833-wb(2).jpg)
- Western Blot analysis of HuvEc cells using Gads Polyclonal Antibody
![](/uploadfiles/PIC/yt1833_pic700318522.jpg)
- Western blot analysis of lysates from HUVEC cells, using GRAP2 Antibody. The lane on the right is blocked with the synthesized peptide.
![](/uploadfiles/PIC/yt1833_pic995418522.jpg)
- Western blot analysis of the lysates from HUVECcells using GRAP2 antibody.