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WB 试剂
- PonceauS Staining Solution
- PBST Washing Buffer, 10X
- 1.5M Tris-HCl Buffer, pH8.8
- 1M Tris-HCl Buffer, pH6.8
- 10% SDS Solution
- Prestained Protein Marker
- TBST Washing Buffer, 10X
- SDS PAGE Loading Buffer, 5X
- Stripping Buffered Solution
- Tris Buffer, pH7.4, 10X
- Total Protein Extraction Kit
- Running Buffer, 10X
- Transfer Buffer, 10X
- 30% Acr-Bis(29:1) Solution
- Tris电泳液速溶颗粒
- PBS(1X, premixed powder)
- TBS(1X, premixed powder)
- 快速封闭液
- 转膜液速溶颗粒
- Chemical reagents
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FPR1 Polyclonal Antibody
- 货号:YT1769
- 应用:WB;IF;ELISA
- 种属:Human;Rat;Mouse;
- 简介:
- >>Rap1 signaling pathway;>>Neuroactive ligand-receptor interaction;>>Neutrophil extracellular trap formation;>>Staphylococcus aureus infection
- 蛋白名称:
- fMet-Leu-Phe receptor
- 免疫原:
- The antiserum was produced against synthesized peptide derived from human FPR1. AA range:151-200
- 特异性:
- FPR1 Polyclonal Antibody detects endogenous levels of FPR1 protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- FPR1;fMet-Leu-Phe receptor;fMLP receptor;N-formyl peptide receptor;FPR;N-formylpeptide chemoattractant receptor
- 背景:
- formyl peptide receptor 1(FPR1) Homo sapiens This gene encodes a G protein-coupled receptor of mammalian phagocytic cells that is a member of the G-protein coupled receptor 1 family. The protein mediates the response of phagocytic cells to invasion of the host by microorganisms and is important in host defense and inflammation.[provided by RefSeq, Jul 2010],
- 功能:
- function:High affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.,PTM:Phosphorylated; which is necessary for desensitization.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Neutrophils.,
- 细胞定位:
- Cell membrane ; Multi-pass membrane protein . Internalizes in presence of its ligands, fMLP, TAFA4 and CTSG. .
![](/uploadfiles/PIC/yt1769_pic839718522.jpg)
- Immunofluorescence analysis of A549 cells, using FPR1 Antibody. The picture on the right is blocked with the synthesized peptide.
![](/uploadfiles/PIC/YT1769wb-2020.jpg)
- Western blot analysis of lysates from DU145 cells, primary antibody was diluted at 1:1000, 4°over night