Eps8L1 Polyclonal Antibody
- 货号:YT1598
- 应用:WB;IHC;IF;ELISA
- 种属:Human;Mouse
- 蛋白名称:
- Epidermal growth factor receptor kinase substrate 8-like protein 1
- 免疫原:
- The antiserum was produced against synthesized peptide derived from human ES8L1. AA range:411-460
- 特异性:
- Eps8L1 Polyclonal Antibody detects endogenous levels of Eps8L1 protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- EPS8L1;DRC3;EPS8R1;PP10566;Epidermal growth factor receptor kinase substrate 8-like protein 1;EPS8-like protein 1;Epidermal growth factor receptor pathway substrate 8-related protein 1;EPS8-related protein 1
- 背景:
- This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. At least two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
- 功能:
- function:Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton.,similarity:Belongs to the EPS8 family.,similarity:Contains 1 SH3 domain.,subunit:Interacts with ABI1. Part of a complex that contains SOS1, ABI1 and EPS8L2. Associates with F-actin.,tissue specificity:Detected in placenta.,
- 组织表达:
- Detected in placenta.
- Western Blot analysis of various cells using Eps8L1 Polyclonal Antibody
- Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using ES8L1 Antibody. The picture on the right is blocked with the synthesized peptide.
- Western blot analysis of lysates from COLO205 and HT-29 cells, using ES8L1 Antibody. The lane on the right is blocked with the synthesized peptide.