- 靶点:
- Endomucin
- 基因名称:
- EMCN
- 蛋白名称:
- Endomucin
- Human Gene Id:
- 51705
- Human Swiss Prot No:
- Q9ULC0
- Mouse Gene Id:
- 59308
- Mouse Swiss Prot No:
- Q9R0H2
- Rat Gene Id:
- 295490
- Rat Swiss Prot No:
- Q6AY82
- 免疫原:
- The antiserum was produced against synthesized peptide derived from human Mucin-14. AA range:201-250
- 特异性:
- Endomucin Polyclonal Antibody detects endogenous levels of Endomucin protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 浓度:
- 1 mg/ml
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- EMCN;EMCN2;MUC14;Endomucin;Endomucin-2;Gastric cancer antigen Ga34;Mucin-14;MUC-14
- 分子量:
- 27kD
- 背景:
- endomucin(EMCN) Homo sapiens EMCN is a mucin-like sialoglycoprotein that interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix (Kinoshita et al., 2001 [PubMed 11418125]).[supplied by OMIM, Mar 2008],
- 功能:
- function:Endothelial sialomucin, also called endomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix.,PTM:Highly O-glycosylated. Sialic acid-rich glycoprotein.,subcellular location:Consistently localized to the plasma membrane and less abundantly to Golgi-like perinuclear stacks.,tissue specificity:Expressed in heart, kidney and lung.,
- 细胞定位:
- [Isoform 1]: Cell membrane; Single-pass type I membrane protein. Membrane; Single-pass type I membrane protein. Consistently localized to the plasma membrane and less abundantly to Golgi-like perinuclear stacks.; [Isoform 2]: Secreted .
- 组织表达:
- Expressed in heart, kidney and lung.
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- 产品图片
- Immunofluorescence analysis of HepG2 cells, using Mucin-14 Antibody. The picture on the right is blocked with the synthesized peptide.