EF-Tu Polyclonal Antibody
- 货号:YT1479
- 应用:WB;IHC;IF;ELISA
- 种属:Human;Mouse;Rat
- 蛋白名称:
- Elongation factor Tu mitochondrial
- 免疫原:
- The antiserum was produced against synthesized peptide derived from human TUFM. AA range:301-350
- 特异性:
- EF-Tu Polyclonal Antibody detects endogenous levels of EF-Tu protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- TUFM;Elongation factor Tu; mitochondrial;EF-Tu;P43
- 背景:
- This gene encodes a protein which participates in protein translation in mitochondria. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency resulting in lactic acidosis and fatal encephalopathy. A pseudogene has been identified on chromosome 17. [provided by RefSeq, Jul 2008],
- 功能:
- disease:Defects in TUFM are the cause of combined oxidative phosphorylation deficiency type 4 (COXPD4) [MIM:610678]. COXPD4 is characterized by neonatal lactic acidosis, rapidly progressive encephalopathy, severely decreased mitochondrial protein synthesis, and combined deficiency of mtDNA-related mitochondrial respiratory chain complexes.,function:This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.,similarity:Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.,
- 组织表达:
- Brain,Cajal-Retzius cell,Heart,Kidney,Liver,Lung,Placenta,P
![](/uploadfiles/PIC/yt1479_pic692518522.jpg)
- Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using TUFM Antibody. The picture on the right is blocked with the synthesized peptide.
![](/uploadfiles/PIC/YT1479-2021.jpg)
- Western Blot analysis of various cell lysis. Primary Antibody was diluted at 1:1000. Secondary antibody(catalog#:RS23920 was diluted at 1:10000