Dvl-3 Polyclonal Antibody
- 货号:YT1425
- 应用:WB;IHC;IF;ELISA
- 种属:Human;Mouse
- 简介:
- >>mTOR signaling pathway;>>Wnt signaling pathway;>>Notch signaling pathway;>>Hippo signaling pathway;>>Signaling pathways regulating pluripotency of stem cells;>>Melanogenesis;>>Cushing syndrome;>>Alzheimer disease;>>Pathways of neurodegeneration - multiple diseases;>>Human papillomavirus infection;>>Pathways in cancer;>>Basal cell carcinoma;>>Breast cancer;>>Hepatocellular carcinoma;>>Gastric cancer
- 蛋白名称:
- Segment polarity protein dishevelled homolog DVL-3
- 免疫原:
- The antiserum was produced against synthesized peptide derived from human DVL3. AA range:326-375
- 特异性:
- Dvl-3 Polyclonal Antibody detects endogenous levels of Dvl-3 protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- DVL3;KIAA0208;Segment polarity protein dishevelled homolog DVL-3;Dishevelled-3;DSH homolog 3
- 背景:
- This gene is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene, dsh. The Drosophila dishevelled gene encodes a cytoplasmic phosphoprotein that regulates cell proliferation. [provided by RefSeq, Jul 2008],
- 功能:
- function:May play a role in the signal transduction pathway mediated by multiple Wnt genes.,similarity:Belongs to the DSH family.,similarity:Contains 1 DEP domain.,similarity:Contains 1 DIX domain.,similarity:Contains 1 PDZ (DHR) domain.,subunit:Interacts (via the PDZ domain) with the C-terminal regions of VANGL1 and VANGL2 (By similarity). Interacts (via the region containing both the PDZ and DEP domains) with LRRFIP2; the DIX domain may inhibit this interaction.,
- 组织表达:
- Bone marrow,Brain,Hippocampus,Placenta,Uterus,
![](/uploadfiles/PIC/yt1425_pic751518522.jpg)
- Western blot analysis of DVL3 Antibody. The lane on the right is blocked with the DVL3 peptide.
![](/uploadfiles/PIC/yt1425_pic751618522.jpg)
- Immunohistochemistry analysis of paraffin-embedded human brain tissue, using DVL3 Antibody. The picture on the right is blocked with the synthesized peptide.
![](/uploadfiles/PIC/yt1425_pic982018522.jpg)
- Western blot analysis of the lysates from Jurkat cells using DVL3 antibody.