• 靶点：
• DREG

• 基因名称：
• GPR126

• 蛋白名称：
• G-protein coupled receptor 126

• Human Gene Id：
• 57211

• Human Swiss Prot No：
• Q86SQ4

• Mouse Gene Id：
• 215798

• Mouse Swiss Prot No：
• Q6F3F9

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human GPR126. AA range:1091-1140

• 特异性：
• DREG Polyclonal Antibody detects endogenous levels of DREG protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• GPR126;DREG;VIGR;G-protein coupled receptor 126;Developmentally regulated G-protein-coupled receptor;Vascular inducible G protein-coupled receptor

• 实测条带：
• 140kD

• 背景：
• This gene, which is upregulated in human umbilical vein endothelial cells, encodes a G protein-coupled receptor. Variations in this gene can affect a person's stature. Multiple transcript variants encoding different proteins have been found for this gene. [provided by RefSeq, Mar 2009],

• 功能：
• function:Orphan receptor.,polymorphism:Genetic variations in GPR126 influences stature as a quantitative trait (STQTL) [MIM:606255]. Adult height is an easily observable and highly heritable complex continuous trait. Because of this, it is a model trait for studying genetic influence on quantitative traits.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 CUB domain.,similarity:Contains 1 GPS domain.,similarity:Contains 1 pentaxin domain.,

• 细胞定位：
• Cell membrane ; Multi-pass membrane protein . Detected on the cell surface of activated but not resting umbilical vein. .

• 组织表达：
• Expressed in placenta and to a lower extent in pancreas and liver. Detected in aortic endothelial cells but not in skin microvascular endothelial cells.

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