• 靶点：
• DHODH

• 简介：
• >>Pyrimidine metabolism;>>Metabolic pathways;>>Biosynthesis of cofactors

• 基因名称：
• DHODH

• 蛋白名称：
• Dihydroorotate dehydrogenase

• Human Gene Id：
• 1723

• Human Swiss Prot No：
• Q02127

• Mouse Swiss Prot No：
• O35435

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human DHODH. AA range:211-260

• 特异性：
• DHODH Polyclonal Antibody detects endogenous levels of DHODH protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• DHODH;Dihydroorotate dehydrogenase;quinone); mitochondrial;DHOdehase;Dihydroorotate oxidase

• 实测条带：
• 48kD

• 背景：
• The protein encoded by this gene catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane. [provided by RefSeq, Jul 2008],

• 功能：
• catalytic activity:(S)-dihydroorotate + O(2) = orotate + H(2)O(2).,cofactor:Binds 1 FAD per subunit.,pathway:Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from HCO(3)(-): step 4/6.,similarity:Belongs to the dihydroorotate dehydrogenase family.,

• 细胞定位：
• Mitochondrion inner membrane ; Single-pass membrane protein .

• 组织表达：
• Skin,Testis,

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