DBP Polyclonal Antibody

    • 货号:YT1297
    • 应用:WB;ELISA
    • 种属:Human;Monkey
      • 靶点:
      • DBP
      • 基因名称:
      • GC
      • 蛋白名称:
      • Vitamin D-binding protein
      • Human Gene Id:
      • 2638
      • Human Swiss Prot No:
      • P02774
      • Mouse Swiss Prot No:
      • P21614
      • 免疫原:
      • Synthesized peptide derived from DBP . at AA range: 90-170
      • 特异性:
      • DBP Polyclonal Antibody detects endogenous levels of DBP protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • GC;Vitamin D-binding protein;DBP;VDB;Gc-globulin;Group-specific component
      • 实测条带:
      • 55kD
      • 背景:
      • The protein encoded by this gene belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. It binds to vitamin D and its plasma metabolites and transports them to target tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011],
      • 功能:
      • function:Multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. In plasma, it carries the vitamin D sterols and prevents polymerization of actin by binding its monomers. DBP associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes.,polymorphism:Over 80 variants of human DBP have been identified. The three most common alleles are called GC*1F, GC*1S, and GC*2. The sequence shown is that of the GC*2 allele.,similarity:Belongs to the ALB/AFP/VDB family.,similarity:Contains 3 albumin domains.,
      • 细胞定位:
      • Secreted .
      • 组织表达:
      • Expressed in the liver. Found in plasma, ascites, cerebrospinal fluid and urine.
      • 产品图片
      • Western Blot analysis of various cells using DBP Polyclonal Antibody
      • Western Blot analysis of COS7 cells using DBP Polyclonal Antibody