CRBP-III Polyclonal Antibody
- 货号：YT1095
- 应用：IHC;IF;ELISA
- 种属：Human
- 蛋白名称：
- Retinol-binding protein 5
- 免疫原：
- The antiserum was produced against synthesized peptide derived from human CRBP III. AA range:10-59
- 特异性：
- CRBP-III Polyclonal Antibody detects endogenous levels of CRBP-III protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- RBP5;Retinol-binding protein 5;Cellular retinol-binding protein III;CRBP-III;HRBPiso
- 背景：
- retinol binding protein 5(RBP5) Homo sapiens The protein encoded by this gene is a cellular retinol-binding protein expressed highly in kidney and liver. Down-regulation of the encoded protein in hepatocellular carcinoma was associated with large tumor size and poor patient survival rates. [provided by RefSeq, Jul 2016],
- 功能：
- domain:Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.,function:Intracellular transport of retinol.,similarity:Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.,tissue specificity:Higher expression in adult kidney and liver and to a lesser extent in adult and fetal spleen, adult lymph nodes and appendix, and fetal liver and kidney. Strongly decreased in hepatocellular carcinoma tissues (at protein level).,
- 组织表达：
- Higher expression in adult kidney and liver and to a lesser extent in adult and fetal spleen, adult lymph nodes and appendix, and fetal liver and kidney. Strongly decreased in hepatocellular carcinoma tissues (at protein level).
- Immunofluorescence analysis of LOVO cells, using CRBP III Antibody. The picture on the right is blocked with the synthesized peptide.
- Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using CRBP III Antibody. The picture on the right is blocked with the synthesized peptide.
