• 靶点：
• COX19

• 简介：
• >>Thermogenesis

• 基因名称：
• COX19

• 蛋白名称：
• Cytochrome c oxidase assembly protein COX19

• Human Gene Id：
• 90639

• Human Swiss Prot No：
• Q49B96

• Mouse Gene Id：
• 68033

• Mouse Swiss Prot No：
• Q8K0C8

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human COX19. AA range:10-59

• 特异性：
• COX19 Polyclonal Antibody detects endogenous levels of COX19 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• COX19;Cytochrome c oxidase assembly protein COX19;hCOX19

• 分子量：
• 10kD

• 背景：
• COX19 encodes a cytochrome c oxidase (COX)-assembly protein. The S. cerevisiae Cox19 protein may play a role in metal transport to the mitochondrial intermembrane space and assembly of complex IV of the mitochondrial respiratory chain (Sacconi et al., 2005 [PubMed 16212937]).[supplied by OMIM, Mar 2008],

• 功能：
• function:May be required for the assembly of mitochondrial cytochrome c oxidase.,similarity:Belongs to the COX19 family.,similarity:Contains 1 CHCH domain.,tissue specificity:Ubiquitously expressed. Highly expressed in skeletal muscle.,

• 细胞定位：
• Cytoplasm, cytosol . Mitochondrion intermembrane space . Mitochondrion . Partitions between mitochondria and the cytosol in a copper-dependent manner. Enriched in the cytosol when intracellular copper concentrations are elevated. .

• 组织表达：
• Ubiquitously expressed. Highly expressed in skeletal muscle.

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