• 靶点：
• CLIP3

• 基因名称：
• CLIP3

• 蛋白名称：
• CAP-Gly domain-containing linker protein 3

• Human Gene Id：
• 25999

• Human Swiss Prot No：
• Q96DZ5

• Mouse Gene Id：
• 76686

• Mouse Swiss Prot No：
• B9EHT4

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human CLIP3. AA range:361-410

• 特异性：
• CLIP3 Polyclonal Antibody detects endogenous levels of CLIP3 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• CLIP3;CLIPR59;CAP-Gly domain-containing linker protein 3;Cytoplasmic linker protein 170-related 59 kDa protein;CLIP-170-related 59 kDa protein;CLIPR-59

• 实测条带：
• 60kD

• 背景：
• This gene encodes a member of the cytoplasmic linker protein 170 family. Members of this protein family contain a cytoskeleton-associated protein glycine-rich domain and mediate the interaction of microtubules with cellular organelles. The encoded protein plays a role in T cell apoptosis by facilitating the association of tubulin and the lipid raft ganglioside GD3. The encoded protein also functions as a scaffold protein mediating membrane localization of phosphorylated protein kinase B. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010],

• 功能：
• domain:Microtubule association is inhibited by the ANK repeats and the Golgi localization region (GoLD).,function:Functions as a cytoplasmic linker protein. Involved in TGN-endosome dynamics.,miscellaneous:The N-terminal half is dispensable for proper Golgi targeting, whereas the GoLD region is required.,similarity:Contains 2 CAP-Gly domains.,similarity:Contains 3 ANK repeats.,subcellular location:Localized to Golgi stacks as well as on tubulovesicular elements juxtaposed to Golgi cisternae.,subunit:Homodimer.,

• 细胞定位：
• Cell membrane ; Lipid-anchor . Cytoplasm . Golgi apparatus, Golgi stack . Localized to Golgi stacks as well as on tubulovesicular elements juxtaposed to Golgi cisternae.

• 组织表达：
• Brain,Skin,Uterus,

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