• 靶点：
• Cks1

• 简介：
• >>Pathways in cancer;>>Small cell lung cancer

• 基因名称：
• CKS1B

• 蛋白名称：
• Cyclin-dependent kinases regulatory subunit 1

• Human Gene Id：
• 1163

• Human Swiss Prot No：
• P61024

• Mouse Gene Id：
• 54124

• Mouse Swiss Prot No：
• P61025

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human CKS1. AA range:10-59

• 特异性：
• Cks1 Polyclonal Antibody detects endogenous levels of Cks1 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• CKS1B;CKS1;PNAS-143;PNAS-16;Cyclin-dependent kinases regulatory subunit 1;CKS-1

• 实测条带：
• 9kD

• 背景：
• CKS1B protein binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. The CKS1B mRNA is found to be expressed in different patterns through the cell cycle in HeLa cells, which reflects a specialized role for the encoded protein. At least two transcript variants have been identified for this gene, and it appears that only one of them encodes a protein. [provided by RefSeq, Sep 2008],

• 功能：
• function:Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.,similarity:Belongs to the CKS family.,subunit:Forms a homohexamer that can probably bind six kinase subunits.,

• 细胞定位：
• cyclin-dependent protein kinase holoenzyme complex,nucleoplasm,SCF ubiquitin ligase complex,

• 组织表达：
• Brain,Muscle,Promyelocytic leukemia,Prostate,Tongue,

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