CDHF11 Polyclonal Antibody
- 货号:YT0826
- 应用:IHC;IF;ELISA
- 种属:Human;Rat;Mouse;
- 蛋白名称:
- Cadherin EGF LAG seven-pass G-type receptor 3
- 免疫原:
- The antiserum was produced against synthesized peptide derived from human CELSR3. AA range:91-140
- 特异性:
- CDHF11 Polyclonal Antibody detects endogenous levels of CDHF11 protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- CELSR3;CDHF11;EGFL1;FMI1;KIAA0812;MEGF2;Cadherin EGF LAG seven-pass G-type receptor 3;Cadherin family member 11;Epidermal growth factor-like protein 1;EGF-like protein 1;Flamingo homolog 1;hFmi1;Multiple epidermal growth factor-
- 背景:
- This gene belongs to the flamingo subfamily, which is included in the cadherin superfamily. The flamingo cadherins consist of nonclassic-type cadherins that do not interact with catenins. They are plasma membrane proteins containing seven epidermal growth factor-like repeats, nine cadherin domains and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic feature of their subfamily. The encoded protein may be involved in the regulation of contact-dependent neurite growth and may play a role in tumor formation. [provided by RefSeq, Jun 2013],
- 功能:
- function:Does not seem to be involved in anion transport.,function:Receptor that may have an important role in cell/cell signaling during nervous system formation.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.,similarity:Contains 1 GPS domain.,similarity:Contains 1 laminin EGF-like domain.,similarity:Contains 1 STAS domain.,similarity:Contains 2 laminin G-like domains.,similarity:Contains 8 EGF-like domains.,similarity:Contains 9 cadherin domains.,tissue specificity:Ubiquitous. Highest levels in kidney and pancreas. Lower expression in heart, skeletal muscle, liver and placenta. Also found in lung and brain.,
- 细胞定位:
- Cell membrane; Multi-pass membrane protein.
- 组织表达:
- Brain,Cord blood,Duodenum,Epithelium,Kidney,Uterus,
- Immunofluorescence analysis of HepG2 cells, using CELSR3 Antibody. The picture on the right is blocked with the synthesized peptide.
- Immunohistochemistry analysis of paraffin-embedded human brain tissue, using CELSR3 Antibody. The picture on the right is blocked with the synthesized peptide.