• 靶点：
• CD88

• 简介：
• >>Neuroactive ligand-receptor interaction;>>Complement and coagulation cascades;>>Neutrophil extracellular trap formation;>>Alcoholic liver disease;>>Staphylococcus aureus infection;>>Coronavirus disease - COVID-19

• 基因名称：
• C5AR1

• 蛋白名称：
• C5a anaphylatoxin chemotactic receptor

• Human Gene Id：
• 728

• Human Swiss Prot No：
• P21730

• Mouse Swiss Prot No：
• P30993

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human N ternal CD88/C5aR. AA range:301-350

• 特异性：
• CD88 Polyclonal Antibody detects endogenous levels of CD88 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• C5AR1;C5AR;C5R1;C5a anaphylatoxin chemotactic receptor;C5a-R;C5aR;CD antigen CD88

• 实测条带：
• 45kD

• 背景：
• function:Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.,PTM:Sulfation plays a critical role in the association of the receptor with C5a, but no significant role in the ability of the receptor to transduce a signal and mobilize calcium in response to a small peptide agonist.,similarity:Belongs to the G-protein coupled receptor 1 family.,

• 功能：
• function:Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.,PTM:Sulfation plays a critical role in the association of the receptor with C5a, but no significant role in the ability of the receptor to transduce a signal and mobilize calcium in response to a small peptide agonist.,similarity:Belongs to the G-protein coupled receptor 1 family.,

• 细胞定位：
• Cell membrane ; Multi-pass membrane protein . Cytoplasmic vesicle . Phosphorylated C5aR colocalizes with ARRB1 and ARRB2 in cytoplasmic vesicles. .

• 组织表达：
• Brain,

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