• 靶点：
• CD272

• 基因名称：
• BTLA

• 蛋白名称：
• B- and T-lymphocyte attenuator

• Human Gene Id：
• 151888

• Human Swiss Prot No：
• Q7Z6A9

• Mouse Swiss Prot No：
• Q7TSA3

• 免疫原：
• Synthetic peptide from human protein at AA range: 101-150

• 特异性：
• CD272 Polyclonal Antibody detects endogenous levels of CD272 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC 1:200 - 1:1000. Flow cytometry: 1:200 - 1:400. ELISA: 1:10000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• BTLA;B- and T-lymphocyte attenuator;B- and T-lymphocyte-associated protein;CD antigen CD272

• 实测条带：
• 36kD

• 背景：
• This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis. [provided by RefSeq, Aug 2011],

• 功能：
• function:Lymphocyte inhibitory receptor which inhibits lymphocytes during immune response.,PTM:N-glycosylated.,PTM:Phosphorylated on Tyr residues by TNFRSF14 and by antigen receptors cross-linking, both inducing association with PTPN6 and PTPN11.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2. Interacts with TNFRSF14/HVEM.,

• 细胞定位：
• Cell membrane ; Single-pass type I membrane protein .

• 组织表达：
• PCR rescued clones,Peripheral blood,Thymus,Trachea,

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