• 靶点：
• CCS

• 简介：
• >>Amyotrophic lateral sclerosis;>>Pathways of neurodegeneration - multiple diseases

• 基因名称：
• CCS

• 蛋白名称：
• Copper chaperone for superoxide dismutase

• Human Gene Id：
• 9973

• Human Swiss Prot No：
• O14618

• Mouse Swiss Prot No：
• Q9WU84

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human CCS. AA range:225-274

• 特异性：
• CCS Polyclonal Antibody detects endogenous levels of CCS protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• CCS;Copper chaperone for superoxide dismutase;Superoxide dismutase copper chaperone

• 实测条带：
• 32kD

• 背景：
• Copper chaperone for superoxide dismutase specifically delivers Cu to copper/zinc superoxide dismutase and may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor. [provided by RefSeq, Jul 2008],

• 功能：
• cofactor:Binds 1 zinc ion per subunit.,cofactor:Binds 2 copper ions per subunit.,function:Delivers copper to copper zinc superoxide dismutase (SOD1).,similarity:Contains 1 HMA domain.,similarity:In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family.,subunit:Homodimer, and heterodimer with SOD1.,tissue specificity:Ubiquitous.,

• 细胞定位：
• Cytoplasm .

• 组织表达：
• Ubiquitous.

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