Casein Kinase I α1/1L Polyclonal Antibody
- 货号:YT0642
- 应用:IHC;IF;WB;ELISA
- 种属:Human;Mouse;Rat
- 靶点:
- Casein Kinase I α1/1L
- 简介:
- >>Wnt signaling pathway;>>Hedgehog signaling pathway;>>Alzheimer disease;>>Pathways of neurodegeneration - multiple diseases;>>Human papillomavirus infection;>>Breast cancer;>>Hepatocellular carcinoma;>>Gastric cancer
- 基因名称:
- CSNK1A1/CSNK1A1L
- 蛋白名称:
- Casein kinase I isoform alpha/Casein kinase I isoform alpha-like
- Human Gene Id:
- 122011/1452
- Human Swiss Prot No:
- Q8N752/P48729
- Rat Gene Id:
- 113927
- Rat Swiss Prot No:
- P97633
- 免疫原:
- The antiserum was produced against synthesized peptide derived from human CKI-alpha1/L. AA range:141-190
- 特异性:
- Casein Kinase I α1/1L Polyclonal Antibody detects endogenous levels of Casein Kinase I α1/1L protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500-2000 IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 浓度:
- 1 mg/ml
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- CSNK1A1L;Casein kinase I isoform alpha-like;CKI-alpha-like;CK1;CSNK1A1;Casein kinase I isoform alpha;CKI-alpha;CK1
- 实测条带:
- 30kD
- 背景:
- catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling.,similarity:Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.,similarity:Contains 1 protein kinase domain.,
- 功能:
- catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling.,similarity:Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.,similarity:Contains 1 protein kinase domain.,
- 细胞定位:
- Cytoplasm .
- 组织表达:
- Testis,
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- 产品图片
- Immunofluorescence analysis of A549 cells, using CKI-alpha1/L Antibody. The picture on the right is blocked with the synthesized peptide.
- Immunohistochemistry analysis of paraffin-embedded human testis tissue, using CKI-alpha1/L Antibody. The picture on the right is blocked with the synthesized peptide.
- Western blot analysis of lysates from SH-SY5Y cells, primary antibody was diluted at 1:1000, 4°over night