Cadherin-22 Polyclonal Antibody
- 货号:YT0598
- 应用:WB;IHC;IF;ELISA
- 种属:Human;Mouse;Rat
- 免疫原:
- The antiserum was produced against synthesized peptide derived from human CDH22. AA range:111-160
- 特异性:
- Cadherin-22 Polyclonal Antibody detects endogenous levels of Cadherin-22 protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- CDH22;C20orf25;Cadherin-22;Pituitary and brain cadherin;PB-cadherin
- 背景:
- This gene is a member of the cadherin superfamily. The gene product is composed of five cadherin repeat domains and a cytoplasmic tail similar to the highly conserved cytoplasmic region of classical cadherins. Expressed predominantly in the brain, this putative calcium-dependent cell adhesion protein may play an important role in morphogenesis and tissue formation in neural and non-neural cells during development and maintenance of the brain and neuroendocrine organs. [provided by RefSeq, Jul 2008],
- 功能:
- function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. PB-cadherins may have a role in the morphological organization of pituitary gland and brain tissues.,similarity:Contains 5 cadherin domains.,
- 细胞定位:
- Cell membrane ; Single-pass type I membrane protein .
- Immunofluorescence analysis of NIH/3T3 cells, using CDH22 Antibody. The picture on the right is blocked with the synthesized peptide.
- Immunohistochemistry analysis of paraffin-embedded human brain tissue, using CDH22 Antibody. The picture on the right is blocked with the synthesized peptide.
- Western blot analysis of lysates from rat brain cells, using CDH22 Antibody. The lane on the right is blocked with the synthesized peptide.