C3aR Polyclonal Antibody

    • 货号:YT0568
    • 应用:IHC;IF;ELISA
    • 种属:Human;Rat;Mouse;
      • 靶点:
      • C3aR
      • 简介:
      • >>Neuroactive ligand-receptor interaction;>>Complement and coagulation cascades;>>Alcoholic liver disease;>>Staphylococcus aureus infection;>>Coronavirus disease - COVID-19
      • 基因名称:
      • C3AR1
      • 蛋白名称:
      • C3a anaphylatoxin chemotactic receptor
      • Human Gene Id:
      • 719
      • Human Swiss Prot No:
      • Q16581
      • Mouse Swiss Prot No:
      • O09047
      • 免疫原:
      • The antiserum was produced against synthesized peptide derived from human C3AR1. AA range:175-224
      • 特异性:
      • C3aR Polyclonal Antibody detects endogenous levels of C3aR protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • C3AR1;AZ3B;C3R1;HNFAG09;C3a anaphylatoxin chemotactic receptor;C3AR;C3a-R
      • 分子量:
      • 54kD
      • 背景:
      • C3a is an anaphylatoxin released during activation of the complement system. The protein encoded by this gene is an orphan G protein-coupled receptor for C3a. Binding of C3a by the encoded receptor activates chemotaxis, granule enzyme release, superoxide anion production, and bacterial opsonization. [provided by RefSeq, May 2016],
      • 功能:
      • function:Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.,PTM:Among the sulfation sites Tyr-174 is essential for binding of C3a anaphylatoxin.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Widely expressed in several differentiated hematopoietic cell lines, in the lung, spleen, ovary, placenta, small intestine, throughout the brain, heart, and endothelial cells. Mostly expressed in lymphoid tissues.,
      • 细胞定位:
      • Cell membrane; Multi-pass membrane protein.
      • 组织表达:
      • Widely expressed in several differentiated hematopoietic cell lines, in the lung, spleen, ovary, placenta, small intestine, throughout the brain, heart, and endothelial cells. Mostly expressed in lymphoid tissues.
      • 产品图片
      • Immunofluorescence analysis of COS7 cells, using C3AR1 Antibody. The picture on the right is blocked with the synthesized peptide.
      • Immunohistochemistry analysis of paraffin-embedded human brain tissue, using C3AR1 Antibody. The picture on the right is blocked with the synthesized peptide.