Brn-3a Polyclonal Antibody
- 货号：YT0529
- 应用：WB;ELISA
- 种属：Human;Mouse;Rat
- 蛋白名称：
- POU domain class 4 transcription factor 1
- 免疫原：
- The antiserum was produced against synthesized peptide derived from human POU4F1. AA range:311-360
- 特异性：
- Brn-3a Polyclonal Antibody detects endogenous levels of Brn-3a protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- POU4F1;BRN3A;RDC1;POU domain; class 4, transcription factor 1;Brain-specific homeobox/POU domain protein 3A;Brain-3A;Brn-3A;Homeobox/POU domain protein RDC-1;Oct-T1
- 背景：
- This gene encodes a member of the POU-IV class of neural transcription factors. This protein is expressed in a subset of retinal ganglion cells and may be involved in the developing sensory nervous system. This protein may also promote the growth of cervical tumors. A translocation of this gene is associated with some adult acute myeloid leukemias. [provided by RefSeq, Mar 2012],
- 功能：
- developmental stage:Expression peaks early in embryogenesis (day 13.5) and is undetectable 14 days after birth.,function:Probable transcription factor which may play a role in the regulation of specific gene expression within a subset of neuronal lineages. May play a role in determining or maintaining the identities of a small subset of visual system neurons.,similarity:Belongs to the POU transcription factor family. Class-4 subfamily.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 POU-specific domain.,tissue specificity:Brain. Seems to be specific to the retina. Present in the developing brain, spinal cord and eye.,
- 细胞定位：
- Nucleus . Cytoplasm .
- 组织表达：
- Expressed in the brain and the retina. Present in the developing brain, spinal cord and eye.
- Western blot analysis of lysates from SW480 cells, primary antibody was diluted at 1:1000, 4°over night
