AQP5 Polyclonal Antibody

    • 货号:YT0293
    • 应用:WB;IHC;IF;ELISA
    • 种属:Human;Rat;Mouse;
      • 靶点:
      • AQP5
      • 简介:
      • >>Salivary secretion
      • 基因名称:
      • AQP5
      • 蛋白名称:
      • Aquaporin-5
      • Human Gene Id:
      • 362
      • Human Swiss Prot No:
      • P55064
      • Mouse Swiss Prot No:
      • Q9WTY4
      • 免疫原:
      • The antiserum was produced against synthesized peptide derived from human AQP5. AA range:194-243
      • 特异性:
      • AQP5 Polyclonal Antibody detects endogenous levels of AQP5 protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • AQP5;Aquaporin-5;AQP-5
      • 实测条带:
      • 35kD
      • 背景:
      • Aquaporin 5 (AQP5) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions. AQP0, AQP2, AQP5, and AQP6 are closely related and all map to 12q13. [provided by RefSeq, Jul 2008],
      • 功能:
      • domain:Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).,function:Forms a water-specific channel. Implicated in the generation of saliva, tears, and pulmonary secretions.,similarity:Belongs to the MIP/aquaporin (TC 1.A.8) family.,
      • 细胞定位:
      • Apical cell membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . Cytoplasmic vesicle membrane ; Multi-pass membrane protein . Hypotonicity increases location at the cell membrane. Phosphorylation decreases location at the cell membrane. .
      • 组织表达:
      • Detected in skin eccrine sweat glands, at the apical cell membrane and at intercellular canaliculi (at protein level).
      • 产品图片
      • Western Blot analysis of various cells using AQP5 Polyclonal Antibody
      • Immunohistochemistry analysis of AQP5 antibody in paraffin-embedded human lung carcinoma tissue.
      • Western blot analysis of lysate from HUVECcells, using AQP5 antibody.