USP28 (Phospho Ser67) rabbit pAb
- 货号:YP1754
- 应用:WB
- 种属:Human;Mouse;Rat
- 蛋白名称:
- USP28 (Phospho-Ser67)
- 免疫原:
- Synthesized peptide derived from human USP28 (Phospho-Ser67)
- 特异性:
- This antibody detects endogenous levels of USP28 (Phospho-Ser67) at Human, Mouse,Rat
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 纯化工艺:
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.4.19.12) (Deubiquitinating enzyme 28) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28)
- 背景:
- The protein encoded by this gene is a deubiquitinase involved in the DNA damage pathway and DNA damage-induced apoptosis. Overexpression of this gene is seen in several cancers. [provided by RefSeq, Oct 2016],
- 功能:
- catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the peptidase C19 family.,similarity:Contains 1 UIM (ubiquitin-interacting motif) repeat.,
- 细胞定位:
- Nucleus, nucleoplasm .
- Immunofluorescence analysis of MCF7 cell. 1,primary Antibody was diluted at 1:100(4°C overnight). 2, Goat Anti Rabbit IgG (H&L) - AFluor 594 Secondary antibody(catalog No: RS3611) was diluted at 1:500(room temperature, 50min).
- Western Blot analysis of various,using primary antibody at 1:1000 dilution. Secondary antibody(catalog#:RS23920) was diluted at 1:10000