• 靶点：
• MOB1

• 简介：
• >>Hippo signaling pathway;>>Hippo signaling pathway - multiple species

• 蛋白名称：
• MOB1 (Thr12)

• Human Gene Id：
• 55233

• Human Swiss Prot No：
• Q9H8S9

• Mouse Gene Id：
• 232157

• Mouse Swiss Prot No：
• Q921Y0

• Rat Gene Id：
• 297387

• Rat Swiss Prot No：
• Q3T1J9

• 免疫原：
• Synthesized phosho peptide around human MOB1 (Thr12)

• 特异性：
• This antibody detects endogenous levels of Human Mouse Rat MOB1 (phospho-Thr12)

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

• 纯化工艺：
• The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• MOB kinase activator 1A (Mob1 alpha) (Mob1A) (Mob1 homolog 1B) (Mps one binder kinase activator-like 1B)

• 实测条带：
• 23kD

• 背景：
• The protein encoded by this gene is a component of the Hippo signaling pathway, which controls organ size and tumor growth by enhancing apoptosis. Loss of the encoded protein results in cell proliferation and cancer formation. The encoded protein is also involved in the control of microtubule stability during cytokinesis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015],

• 功能：
• function:Stimulates the kinase activity of STK38 and STK38L.,PTM:Phosphorylated.,similarity:Belongs to the MOB1/phocein family.,subunit:Binds STK38 and STK38L.,

• 细胞定位：
• cytosol,extracellular exosome,

• 组织表达：
• Adrenal gland, bone marrow, brain, placenta, prostate, salivary gland, skeletal muscle, testis, thymus, thyroid gland, heart, spinal cord, fetal brain and fetal liver.

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