• 靶点：
• Casein Kinase Iγ1/2/3

• 简介：
• >>Hedgehog signaling pathway

• 基因名称：
• CSNK1G1/CSNK1G2/CSNK1G3

• 蛋白名称：
• Casein kinase I isoform gamma-1/2/3

• Human Gene Id：
• 53944/1455/1456

• Human Swiss Prot No：
• Q9HCP0/P78368/Q9Y6M4

• Mouse Gene Id：
• 214897/103236/70425

• Rat Gene Id：
• 64086/65278/64823

• Rat Swiss Prot No：
• Q62761/Q62762/Q62763

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human CK-1 gamma1/2/3 around the phosphorylation site of Tyr263. AA range:229-278

• 特异性：
• Phospho-Casein Kinase Iγ1/2/3 (Y263) Polyclonal Antibody detects endogenous levels of Casein Kinase Iγ1/2/3 protein only when phosphorylated at Y263.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• CSNK1G1;Casein kinase I isoform gamma-1;CKI-gamma 1;CSNK1G2;CK1G2;Casein kinase I isoform gamma-2;CKI-gamma 2;CSNK1G3;Casein kinase I isoform gamma-3;CKI-gamma 3

• 分子量：
• 50kD

• 背景：
• This gene encodes a member of the casein kinase I gene family. This family is comprised of serine/threonine kinases that phosphorylate acidic proteins such as caseins. The encoded kinase plays a role in cell cycle checkpoint arrest in response to stalled replication forks by phosphorylating Claspin. A mutation in this gene may be associated with non-syndromic early-onset epilepsy (NSEOE). [provided by RefSeq, Jul 2016],

• 功能：
• catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Monomer.,

• 细胞定位：
• Cytoplasm.

• 组织表达：
• Brain,Muscle,Pooled,

• June 19-2018
• WESTERN IMMUNOBLOTTING PROTOCOL

• June 19-2018
• IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL

• June 19-2018
• IMMUNOFLUORESCENCE PROTOCOL

• September 08-2020
• FLOW-CYTOMEYRT-PROTOCOL

• May 20-2022
• Cell-Based ELISA│解您多样本WB检测之困扰

• July 13-2018
• CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN

• July 13-2018
• CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN

• July 13-2018
• CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN

• July 13-2018
• Antibody-FAQs