IPP-2 (phospho Ser120/S121) Polyclonal Antibody

    • 货号:YP1011
    • 应用:IHC;IF;ELISA
    • 种属:Human;Mouse;Rat
      • 靶点:
      • IPP-2
      • 基因名称:
      • PPP1R2
      • 蛋白名称:
      • Protein phosphatase inhibitor 2
      • Human Gene Id:
      • 5504
      • Human Swiss Prot No:
      • P41236
      • Mouse Swiss Prot No:
      • Q9DCL8
      • 免疫原:
      • The antiserum was produced against synthesized peptide derived from human PPP1R2 around the phosphorylation site of Ser120 and Ser121. AA range:86-135
      • 特异性:
      • Phospho-IPP-2 (S120/S121) Polyclonal Antibody detects endogenous levels of IPP-2 protein only when phosphorylated at S120/S121.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • PPP1R2;IPP2;Protein phosphatase inhibitor 2;IPP-2
      • 分子量:
      • 23kD
      • 背景:
      • Protein phosphatase-1 (PP1) is one of the main eukaryotic serine/threonine phosphatases. The protein encoded by this gene binds to the catalytic subunit of PP1, strongly inhibiting its activity. Ten related pseudogenes have been found throughout the human genome. Several splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015],
      • 功能:
      • function:Inhibitor of protein-phosphatase 1.,PTM:Phosphorylation on Thr-73 by GSK3 activates PP1 by dissociating the PP1-PPP1R2 complex (By similarity). Phosphorylation on Ser-44 by ATM activates PP1 by dissociating the PP1-PPP1R2 complex.,similarity:Belongs to the protein phosphatase inhibitor 2 family.,subunit:Heterodimer with PP1.,
      • 细胞定位:
      • protein phosphatase type 1 complex,
      • 组织表达:
      • Epithelium,Heart,Platelet,Skin,Testis,
      • 产品图片
      • Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using PPP1R2 (Phospho-Ser120+Ser121) Antibody
      • Immunohistochemistry analysis of paraffin-embedded human heart, using PPP1R2 (Phospho-Ser120+Ser121) Antibody. The picture on the right is blocked with the phospho peptide.