• 靶点：
• DNAM-1

• 简介：
• >>Cell adhesion molecules

• 基因名称：
• CD226

• 蛋白名称：
• CD226 antigen

• Human Gene Id：
• 10666

• Human Swiss Prot No：
• Q15762

• Mouse Gene Id：
• 225825

• Mouse Swiss Prot No：
• Q8K4F0

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human CD226/DNAM-1 around the phosphorylation site of Ser329. AA range:287-336

• 特异性：
• Phospho-DNAM-1 (S329) Polyclonal Antibody detects endogenous levels of DNAM-1 protein only when phosphorylated at S329.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• CD226;DNAM1;CD226 antigen;DNAX accessory molecule 1;DNAM-1;CD antigen CD226

• 实测条带：
• 60kD

• 背景：
• This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015],

• 功能：
• function:Receptor involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell.,PTM:Phosphorylated.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Interacts with PVR and PVRL2.,tissue specificity:Expressed by peripheral blood T-lymphocytes.,

• 细胞定位：
• Cell membrane ; Single-pass type I membrane protein .

• 组织表达：
• Expressed by peripheral blood T-lymphocytes.

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