ARPC4 rabbit pAb

  • 货号：YN7252
  • 应用：WB
  • 种属：Human;Mouse
    • 靶点：
    • ARPC4
    • 基因名称：
    • ARPC4 ARC20
    • 蛋白名称：
    • Actin-related protein 2/3 complex subunit 4 (Arp2/3 complex 20 kDa subunit) (p20-ARC)
    • Human Swiss Prot No：
    • P59998
    • Mouse Swiss Prot No：
    • P59999
    • 免疫原：
    • Synthesized peptide derived from human ARPC4
    • 特异性：
    • This antibody detects endogenous levels of ARPC4 at Human, Mouse
    • 组成：
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • 来源：
    • Polyclonal, Rabbit,IgG
    • 稀释：
    • WB 1:500-2000
    • 纯化工艺：
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • 浓度：
    • 1 mg/ml
    • 储存：
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • 分子量：
    • 18kD
    • 功能：
    • Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) . The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility . In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA . The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) .
    • 细胞定位：
    • Cytoplasm, cytoskeleton . Cell projection . Nucleus .

    相关报价

    • 货号：
    • YN7252
    • 规格：
    • 40μL / 100μL / 200μL
    • 价格：
    • ¥960 / 2300 / 3780
    • 货期：
    • 预计发货时间为
      2024-07-26
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