CCM2 rabbit pAb

  • 货号:YN7246
  • 应用:WB
  • 种属:Human;Mouse
    • 靶点:
    • CCM2
    • 基因名称:
    • CCM2 C7orf22 PP10187
    • 蛋白名称:
    • Malcavernin (Cerebral cavernous malformations 2 protein)
    • Human Swiss Prot No:
    • Q9BSQ5
    • Mouse Swiss Prot No:
    • Q8K2Y9
    • 免疫原:
    • Synthesized peptide derived from human CCM2
    • 特异性:
    • This antibody detects endogenous levels of CCM2 at Human, Mouse
    • 组成:
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • 来源:
    • Polyclonal, Rabbit,IgG
    • 稀释:
    • WB 1:500-2000
    • 纯化工艺:
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • 浓度:
    • 1 mg/ml
    • 储存:
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • 分子量:
    • 49kD
    • 功能:
    • Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May act through the stabilization of endothelial cell junctions (By similarity). May function as a scaffold protein for MAP2K3-MAP3K3 signaling. Seems to play a major role in the modulation of MAP3K3-dependent p38 activation induced by hyperosmotic shock (By similarity).
    • 细胞定位:
    • Cytoplasm .