PHF20 rabbit pAb

  • 货号:YN7242
  • 应用:WB
  • 种属:Human;Mouse
    • 靶点:
    • PHF20
    • 基因名称:
    • PHF20 C20orf104 GLEA2 HCA58 NZF TZP
    • 蛋白名称:
    • PHD finger protein 20 (Glioma-expressed antigen 2) (Hepatocellular carcinoma-associated antigen 58) (Novel zinc finger protein) (Transcription factor TZP)
    • Human Swiss Prot No:
    • Q9BVI0
    • Mouse Swiss Prot No:
    • Q8BLG0
    • 免疫原:
    • Synthesized peptide derived from human PHF20
    • 特异性:
    • This antibody detects endogenous levels of PHF20 at Human, Mouse
    • 组成:
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • 来源:
    • Polyclonal, Rabbit,IgG
    • 稀释:
    • WB 1:500-2000
    • 纯化工艺:
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • 浓度:
    • 1 mg/ml
    • 储存:
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • 分子量:
    • 111kD
    • 功能:
    • Methyllysine-binding protein, component of the MOF histone acetyltransferase protein complex. Not required for maintaining the global histone H4 'Lys-16' acetylation (H4K16ac) levels or locus specific histone acetylation, but instead works downstream in transcriptional regulation of MOF target genes (By similarity). As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Contributes to methyllysine-dependent p53/TP53 stabilization and up-regulation after DNA damage.
    • 细胞定位:
    • Nucleus .
    • 组织表达:
    • Expressed in heart, kidney, liver, lung, pancreas, placenta, spleen and testis. Not expressed in brain, skeletal muscle, colon, ovary, prostate, small intestine and thymus. Expressed in colon and ovary cancer cell lines while it is not expressed in the respective normal tissues.