EML1 rabbit pAb

  • 货号:YN7232
  • 应用:WB
  • 种属:Human;Mouse;Rat
    • 靶点:
    • EML1
    • 基因名称:
    • EML1 EMAP1 EMAPL EMAPL1
    • 蛋白名称:
    • Echinoderm microtubule-associated protein-like 1 (EMAP-1) (HuEMAP-1)
    • Human Gene Id:
    • 2009
    • Human Swiss Prot No:
    • O00423
    • Mouse Swiss Prot No:
    • Q05BC3
    • 免疫原:
    • Synthesized peptide derived from human EML1
    • 特异性:
    • This antibody detects endogenous levels of EML1 at Human, Mouse,Rat
    • 组成:
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • 来源:
    • Polyclonal, Rabbit,IgG
    • 稀释:
    • WB 1:500-2000
    • 纯化工艺:
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • 浓度:
    • 1 mg/ml
    • 储存:
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • 分子量:
    • 90kD
    • 功能:
    • Modulates the assembly and organization of the microtubule cytoskeleton, and probably plays a role in regulating the orientation of the mitotic spindle and the orientation of the plane of cell division. Required for normal proliferation of neuronal progenitor cells in the developing brain and for normal brain development. Does not affect neuron migration per se.
    • 细胞定位:
    • Cytoplasm . Cytoplasm, perinuclear region . Cytoplasm, cytoskeleton . Detected in cytoplasmic punctae. Co-localizes with microtubules (PubMed:24859200, PubMed:25740311). Enriched in perinuclear regions during interphase and in the region of spindle microtubules during metaphase. Enriched at the midzone during telophase and cytokinesis. Detected at growth cones in neurons (By similarity). .
    • 组织表达:
    • Ubiquitous; expressed in most tissues with the exception of thymus and peripheral blood lymphocytes.