PEPC Polyclonal Antibody

    • 货号：YN5494
    • 应用：WB
    • 种属： A. comosus, A. thaliana, H. vulgare, J. curcas, M. crystallinum, N. tabacum, Z. mays, T. weissfloggi,
      • 靶点：
      • Phosphoenolpyruvate carboxylase
      • 基因名称：
      • PGC
      • 蛋白名称：
      • Phosphoenolpyruvate carboxylase
      • 免疫原：
      • Synthetic Peptide of PEPC
      • 特异性：
      • The antibody detects endogenous PEPC protein.
      • 组成：
      • PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
      • 来源：
      • Polyclonal, Rabbit,IgG
      • 稀释：
      • WB 1:2000-5000
      • 纯化工艺：
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 储存：
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称：
      • PGC;Gastricsin;Pepsinogen C
      • 实测条带：
      • 105-109kD
      • 背景：
      • This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009],
      • 功能：
      • catalytic activity:More restricted specificity than pepsin A, but shows preferential cleavage at Tyr-|-Xaa bonds. High activity on hemoglobin.,function:Hydrolyzes a variety of proteins.,similarity:Belongs to the peptidase A1 family.,
      • 细胞定位：
      • extracellular space,extracellular exosome,
      • 组织表达：
      • Brain,Liver,Placenta,Stomach,
      • 产品图片
      • Western blot analysis of Maize, diluted at 1:4000. Secondary antibody(catalog#:RS0002) was diluted at 1:20000

      相关报价

      • 货号：
      • YN5494
      • 规格：
      • 40μL / 100μL / 200μL
      • 价格：
      • ¥960 / 2300 / 3780
      • 货期：
      • 预计发货时间为
        2024-07-19
      订购

      相关产品