ANXA5 Polyclonal Antibody
- 货号：YN2326
- 应用：WB;ELISA
- 种属：Human;Mouse;Rat
- 基因名称：
- ANXA5 ANX5 ENX2 PP4
- 蛋白名称：
- Annexin A5 (Anchorin CII) (Annexin V) (Annexin-5) (Calphobindin I) (CBP-I) (Endonexin II) (Lipocortin V) (Placental anticoagulant protein 4) (PP4) (Placental anticoagulant protein I) (PAP-I) (Thrombop
- 免疫原：
- Synthesized peptide derived from human protein . at AA range: 60-140
- 特异性：
- ANXA5 Polyclonal Antibody detects endogenous levels of protein.
- 组成：
- Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500-2000 ELISA 1:5000-20000
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 背景：
- The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. The gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa. [provided by RefSeq, Jul 2008],
- 功能：
- caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,caution:This protein has been independently sequenced by at least seven groups under different names.,domain:A pair of annexin repeats may form one binding site for calcium and phospholipid.,function:This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.,similarity:Belongs to the annexin family.,similarity:Contains 4 annexin repeats.,subunit:Monomer. Binds ATRX and EIF5B.,
- 细胞定位：
- intracellular,cytoplasm,focal adhesion,external side of plasma membrane,membrane,extracellular exosome,endothelial microparticle,
- 组织表达：
- Adipocyte,Epithelium,Lung,Melanoma,Muscle,Ovary,Placenta,Skin,
- Western blot analysis of lysates from HCT116 cells, primary antibody was diluted at 1:1000, 4°over night
