Iba1 Polyclonal Antibody

  • 货号:YN2165
  • 应用:WB;IF;ELISA
  • 种属:Human;Rat;Mouse
    • 靶点:
    • AIF1
    • 基因名称:
    • AIF1 G1 IBA1
    • 蛋白名称:
    • Allograft inflammatory factor 1 (AIF-1) (Ionized calcium-binding adapter molecule 1) (Protein G1)
    • Human Gene Id:
    • 199
    • Human Swiss Prot No:
    • P55008
    • Mouse Swiss Prot No:
    • O70200
    • 免疫原:
    • Synthesized peptide derived from part region of human protein
    • 特异性:
    • AIF1 Polyclonal Antibody detects endogenous levels of protein.
    • 组成:
    • Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
    • 来源:
    • Polyclonal, Rabbit,IgG
    • 稀释:
    • WB 1:500 - 1:2000. ELISA: 1:5000. IF 1:100-300 Not yet tested in other applications.
    • 纯化工艺:
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • 浓度:
    • 1 mg/ml
    • 储存:
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • 实测条带:
    • 16kD
    • 背景:
    • This gene encodes a protein that binds actin and calcium. This gene is induced by cytokines and interferon and may promote macrophage activation and growth of vascular smooth muscle cells and T-lymphocytes. Polymorphisms in this gene may be associated with systemic sclerosis. Alternative splicing results in multiple transcript variants, but the full-length and coding nature of some of these variants is not certain. [provided by RefSeq, Jan 2016],
    • 功能:
    • function:May play a role in macrophage activation and function.,PTM:Phosphorylated on serine residues.,similarity:Contains 2 EF-hand domains.,
    • 细胞定位:
    • Cytoplasm, cytoskeleton . Cell projection, ruffle membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection, phagocytic cup . Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis. .
    • 组织表达:
    • Detected in T-lymphocytes and peripheral blood mononuclear cells.