RASA2 Polyclonal Antibody

  • 货号:YN1855
  • 应用:WB;ELISA
  • 种属:Human;Mouse;Rat
    • 靶点:
    • RASA2
    • 简介:
    • >>MAPK signaling pathway;>>Ras signaling pathway;>>Viral carcinogenesis
    • 基因名称:
    • RASA2 GAP1M RASGAP
    • 蛋白名称:
    • Ras GTPase-activating protein 2 (GAP1m)
    • Human Gene Id:
    • 5922
    • Human Swiss Prot No:
    • Q15283
    • Mouse Swiss Prot No:
    • P58069
    • 免疫原:
    • Synthesized peptide derived from part region of human protein
    • 特异性:
    • RASA2 Polyclonal Antibody detects endogenous levels of protein.
    • 组成:
    • Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
    • 来源:
    • Polyclonal, Rabbit,IgG
    • 稀释:
    • WB 1:500-2000 ELISA 1:5000-20000
    • 纯化工艺:
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • 浓度:
    • 1 mg/ml
    • 储存:
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • 实测条带:
    • 93kD
    • 背景:
    • The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014],
    • 功能:
    • function:Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4).,similarity:Contains 1 Btk-type zinc finger.,similarity:Contains 1 PH domain.,similarity:Contains 1 Ras-GAP domain.,similarity:Contains 2 C2 domains.,
    • 细胞定位:
    • Cytoplasm. Cytoplasm, perinuclear region.
    • 组织表达:
    • Blood,Brain,