• 靶点：
• IFNK

• 简介：
• >>Cytokine-cytokine receptor interaction;>>RIG-I-like receptor signaling pathway;>>JAK-STAT signaling pathway

• 基因名称：
• IFNK UNQ6124/PRO20084

• 蛋白名称：
• Interferon kappa (IFN-kappa)

• Human Gene Id：
• 56832

• Human Swiss Prot No：
• Q9P0W0

• Mouse Swiss Prot No：
• Q7TSL0

• 免疫原：
• Synthesized peptide derived from human protein . at AA range: 70-150

• 特异性：
• IFNK Polyclonal Antibody detects endogenous levels of protein.

• 组成：
• Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500-2000 ELISA 1:5000-20000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 实测条带：
• 22kD

• 背景：
• This gene encodes a member of the type I interferon family. Type I interferons are a group of related glycoproteins that play an important role in host defenses against viral infections. This protein is expressed in keratinocytes and the gene is found on chromosome 9, adjacent to the type I interferon cluster. [provided by RefSeq, Jul 2008],

• 功能：
• function:May play a role in the regulation of immune cell function. Cytokine that imparts cellular protection against viral infection in a species-specific manner. Activates the interferon-stimulated response element signaling pathway. It is able to directly modulate cytokine release from monocytes and dendritic cells. Binds heparin.,induction:By viral infection, upon exposure to double-stranded RNA, or upon treatment with either interferon-gamma or interferon-beta.,similarity:Belongs to the alpha/beta interferon family.,tissue specificity:Expressed in keratinocytes, monocytes and in resting dendritic cells.,

• 细胞定位：
• Secreted.

• 组织表达：
• Expressed in keratinocytes, monocytes and in resting dendritic cells.

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